Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | TP53 | P04637 | 8/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960878 | 1.00 | MAPT (0.57) | MAPTTP53GAAPOLBHTR6 | |
| SCHEMBL30908989 | 0.91 | MAPT (0.57) | MAPTTP53GAAPOLBHTR6 | |
| SCHEMBL6958342 | 0.91 | MAPT (0.57) | MAPTTP53GAAPOLBHTR6 | |
| SCHEMBL6953187 | 0.90 | MAPT (0.58) | MAPTTP53GAAPOLBHTR6 | |
| SCHEMBL6957023 | 0.89 | MAPT (0.55) | MAPTTP53GAAPOLBHTR6 | |
| SCHEMBL30908784 | 0.89 | MAPT (0.55) | MAPTTP53GAAPOLBHTR6 | |
| SCHEMBL6949289 | 0.87 | MAPT (0.51) | MAPTTP53GAAPOLBHTR6 | |
| SCHEMBL30909109 | 0.87 | MAPT (0.51) | MAPTTP53GAAPOLBHTR6 | |
| SCHEMBL6958103 | 0.85 | MAPT (0.52) | MAPTTP53GAAPOLBHTR6 | |
| SCHEMBL30909012 | 0.85 | MAPT (0.52) | MAPTTP53GAAPOLBHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |