Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.52 |
| ▸ | TP53 | P04637 | 8/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HTR1F | P30939 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6958103 | 1.00 | MAPT (0.52) | MAPTTP53SMN1; SMN2THRBPOLB | |
| SCHEMBL6949289 | 0.89 | MAPT (0.51) | MAPTTP53SMN1; SMN2THRBPOLB | |
| SCHEMBL30909109 | 0.89 | MAPT (0.51) | MAPTTP53SMN1; SMN2THRBPOLB | |
| SCHEMBL6960878 | 0.85 | MAPT (0.57) | MAPTTP53SMN1; SMN2THRBPOLB | |
| SCHEMBL30908855 | 0.85 | MAPT (0.57) | MAPTTP53SMN1; SMN2THRBPOLB | |
| SCHEMBL30908989 | 0.84 | MAPT (0.57) | MAPTTP53SMN1; SMN2THRBPOLB | |
| SCHEMBL6958342 | 0.84 | MAPT (0.57) | MAPTTP53SMN1; SMN2THRBPOLB | |
| SCHEMBL6953187 | 0.83 | MAPT (0.58) | MAPTTP53SMN1; SMN2THRBPOLB | |
| SCHEMBL30909221 | 0.81 | HTR1F (0.43) | MAPTTP53SMN1; SMN2THRBPOLB | |
| SCHEMBL6962292 | 0.81 | HTR1F (0.43) | MAPTTP53SMN1; SMN2THRBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |