Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.30 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30909167 | 0.87 | HRH3 (0.38) | HRH3OPRM1OPRK1L3MBTL1 | |
| SCHEMBL8720752 | 0.83 | MEN1 (0.38) | HRH3L3MBTL1 | |
| SCHEMBL8724259 | 0.83 | HRH3 (0.39) | HRH3OPRM1OPRK1L3MBTL3L3MBTL1 | |
| SCHEMBL35210767 | 0.83 | TDP1 (0.41) | HRH3OPRM1OPRK1KDM2BHTR1D | |
| SCHEMBL8724062 | 0.83 | HRH3 (0.40) | HRH3OPRM1OPRK1KDM2BHTR1D | |
| SCHEMBL8721871 | 0.82 | HRH3 (0.40) | HRH3OPRM1OPRK1KDM2BCNR1 | |
| Sebacic Acid SCHEMBL8721076 | 0.82 | HRH3 (0.38) | HRH3OPRM1OPRK1KDM2B | |
| SCHEMBL8720766 | 0.81 | HRH3 (0.38) | HRH3CNR2 | |
| SCHEMBL8724068 | 0.79 | KDM4E (0.43) | — | |
| SCHEMBL8721851 | 0.77 | TDP1 (0.38) | L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |