Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30909167 | 0.87 | HRH3 (0.38) | KMT2ALMNAKDM4EHTTL3MBTL1 | |
| SCHEMBL8723878 | 0.87 | NR1H4 (0.46) | MEN1KMT2ALMNAKDM4EALOX12 | |
| SCHEMBL8720693 | 0.85 | NPC1 (0.44) | MEN1KMT2ALMNATDP1NPSR1 | |
| Iodide SCHEMBL8723627 | 0.85 | HRH3 (0.34) | HRH3CYP2D6CYP2C19NPSR1TSHR | |
| SCHEMBL30908873 | 0.83 | HRH3 (0.39) | L3MBTL1HRH3 | |
| SCHEMBL35210767 | 0.83 | TDP1 (0.41) | KMT2ALMNAKDM4EHTTTDP1 | |
| SCHEMBL8724062 | 0.83 | HRH3 (0.40) | MEN1KMT2AL3MBTL1HRH3 | |
| Hydrochloric Acid SCHEMBL8706194 | 0.82 | NPSR1 (0.35) | KMT2AHRH3CYP2D6CYP2C19NPSR1 | |
| SCHEMBL8720766 | 0.81 | HRH3 (0.38) | LMNAHRH3HPGDMAPT | |
| Sebacic Acid SCHEMBL8721076 | 0.79 | HRH3 (0.38) | MEN1KMT2AHRH3NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |