Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8382137 | 1.00 | MAPT (0.41) | MAPTLMNANOS3NOS1BTK | |
| SCHEMBL30909253 | 0.91 | MAPT (0.41) | MAPTLMNANOS3NOS1POLB | |
| SCHEMBL8381665 | 0.91 | MAPT (0.41) | MAPTLMNANOS3NOS1POLB | |
| SCHEMBL8386453 | 0.86 | MAPT (0.40) | MAPTLMNANOS3NOS1BTK | |
| SCHEMBL30908852 | 0.86 | MAPT (0.40) | MAPTLMNANOS3NOS1BTK | |
| SCHEMBL8381739 | 0.86 | NOS3 (0.40) | MAPTNOS3NOS1 | |
| SCHEMBL5906286 | 0.85 | ITK (0.41) | ROCK2NPY2R | |
| SCHEMBL8387372 | 0.84 | NOS3 (0.44) | MAPTLMNANOS3NOS1 | |
| SCHEMBL8383483 | 0.82 | MAPT (0.47) | MAPTNOS3NOS1POLB | |
| SCHEMBL8385402 | 0.81 | MAPT (0.41) | MAPTLMNANOS3NOS1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |