Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.65 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8116686 | 1.00 | HTR1F (0.65) | HTR1FRORCLRRK2KMT2AMEN1 | |
| SCHEMBL7656996 | 0.88 | HTR1F (0.68) | HTR1FKMT2AMEN1MAPTHPGD | |
| SCHEMBL7663021 | 0.87 | HTR1F (0.67) | HTR1FKMT2AMEN1MAPTHPGD | |
| SCHEMBL7658859 | 0.87 | HTR1F (0.73) | HTR1FKMT2AMEN1MAPTHPGD | |
| SCHEMBL8116194 | 0.86 | HTR1F (0.49) | HTR1FRORCLRRK2KMT2AMEN1 | |
| SCHEMBL30909185 | 0.86 | HTR1F (0.49) | HTR1FRORCLRRK2KMT2AMEN1 | |
| SCHEMBL7654358 | 0.86 | HTR1F (0.66) | HTR1FKMT2AMEN1MAPTHPGD | |
| SCHEMBL7656434 | 0.85 | HTR1F (0.68) | HTR1FKMT2AMEN1MAPTKDM4E | |
| SCHEMBL7656398 | 0.84 | HTR1F (0.81) | HTR1FKMT2AMEN1MAPTHPGD | |
| SCHEMBL7660418 | 0.84 | HTR1F (0.78) | HTR1FRORCLRRK2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |