Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.47 |
| ▸ | NOS3 | P29474 | 2/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490577 | 1.00 | NR1H4 (0.47) | NR1H4NOS3NOS1MAPTTSHR | |
| SCHEMBL7485012 | 0.90 | NOS3 (0.48) | NR1H4NOS3NOS1MAPTTSHR | |
| SCHEMBL7488215 | 0.88 | NOS3 (0.50) | NR1H4NOS3NOS1MAPTTSHR | |
| SCHEMBL30908811 | 0.88 | NOS3 (0.50) | NR1H4NOS3NOS1MAPTTSHR | |
| SCHEMBL30908773 | 0.88 | NR1H4 (0.48) | NR1H4NOS3NOS1MAPTTSHR | |
| SCHEMBL7483920 | 0.88 | NR1H4 (0.48) | NR1H4NOS3NOS1MAPTTSHR | |
| SCHEMBL7478489 | 0.87 | NOS3 (0.51) | NR1H4NOS3NOS1MAPTTSHR | |
| SCHEMBL7477471 | 0.87 | NOS3 (0.46) | NR1H4NOS3NOS1MAPTHTR1A | |
| SCHEMBL7485020 | 0.85 | NOS3 (0.50) | NR1H4NOS3NOS1MAPTTSHR | |
| SCHEMBL7483337 | 0.85 | NOS3 (0.62) | NOS3NOS1MAPTHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |