Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 17/20 | 0.48 |
| ▸ | HTR1D | P28221 | 10/20 | 0.40 |
| ▸ | HTR1B | P28222 | 8/20 | 0.40 |
| ▸ | HTR1A | P08908 | 7/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR1E | P28566 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721234 | 1.00 | HTR1F (0.48) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8725940 | 0.93 | HTR1F (0.51) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL30908959 | 0.93 | HTR1F (0.51) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8724112 | 0.85 | HTR1D (0.41) | HTR1DHTR1B | |
| SCHEMBL30909115 | 0.84 | HTR1F (0.54) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8724225 | 0.84 | HTR1F (0.54) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8385535 | 0.83 | HTR1F (0.46) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8386478 | 0.80 | HTR1F (0.48) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8383688 | 0.78 | HTR1F (0.49) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL30908995 | 0.78 | HTR1F (0.54) | HTR1FHTR1DHTR1BHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |