Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7008254 | 1.00 | HTR1F (0.44) | HTR1FKDRSLC6A4KDM4ELMNA | |
| SCHEMBL30908825 | 0.79 | HTR1F (0.48) | HTR1FSLC6A4KDM4ELMNAPOLB | |
| SCHEMBL7007191 | 0.79 | HTR1F (0.48) | HTR1FSLC6A4KDM4ELMNAPOLB | |
| SCHEMBL7101114 | 0.78 | HTR1F (0.55) | HTR1FHTR1AHTR6 | |
| SCHEMBL30909240 | 0.78 | HTR1F (0.55) | HTR1FHTR1AHTR6 | |
| SCHEMBL7014305 | 0.78 | HTR1F (0.47) | HTR1FSLC6A4KDM4ELMNAPOLB | |
| SCHEMBL30908999 | 0.78 | HTR1F (0.47) | HTR1FSLC6A4KDM4ELMNAPOLB | |
| SCHEMBL7012821 | 0.78 | HTR1F (0.47) | HTR1FSLC6A4KDM4ELMNAPOLB | |
| SCHEMBL30908981 | 0.78 | HTR1F (0.47) | HTR1FSLC6A4KDM4ELMNAPOLB | |
| SCHEMBL7010491 | 0.77 | HTR1F (0.49) | HTR1FSLC6A4KDM4ELMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |