Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8383718 | 1.00 | NOS3 (0.43) | NOS3NOS1RORCCDK2GSK3B | |
| SCHEMBL8387372 | 0.85 | NOS3 (0.44) | NOS3NOS1MAPTLMNA | |
| SCHEMBL8386628 | 0.84 | NOS3 (0.40) | NOS3NOS1RORCMAPTLMNA | |
| SCHEMBL8386551 | 0.83 | NOS3 (0.54) | NOS3NOS1RORCMAPTLMNA | |
| Hydrochloric Acid SCHEMBL8386484 | 0.82 | NOS3 (0.56) | NOS3NOS1RORCMAPTLMNA | |
| SCHEMBL8383851 | 0.81 | MAPT (0.45) | NOS3NOS1MAPTLMNAPOLB | |
| SCHEMBL8385392 | 0.81 | MAPT (0.45) | NOS3NOS1MAPTLMNA | |
| SCHEMBL8382132 | 0.81 | HTR1D (0.40) | NOS3NOS1SLC6A4MAPTPOLB | |
| SCHEMBL8386497 | 0.81 | NOS3 (0.40) | NOS3NOS1MAPTLMNAPOLB | |
| SCHEMBL8382850 | 0.80 | NOS3 (0.41) | NOS3NOS1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |