Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 3/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | PER2 | O15055 | 1/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26089588 | 1.00 | AVPR1A (0.41) | AVPR1APIM1BRD4MMP2MMP9 | |
| SCHEMBL27506539 | 0.90 | AVPR1A (0.40) | AVPR1APIM1BRD4MMP2MMP9 | |
| SCHEMBL4793671 | 0.81 | BRD4 (0.41) | AVPR1APIM1BRD4BRPF1MEN1 | |
| SCHEMBL14497763 | 0.78 | MEN1 (0.49) | AVPR1APIM1BRD4BRPF1MEN1 | |
| SCHEMBL28833095 | 0.77 | EPHX2 (0.38) | AVPR1APIM1BRD4MMP2BRPF1 | |
| SCHEMBL28187925 | 0.77 | AVPR1A (0.44) | AVPR1APIM1BRD4MMP2MMP9 | |
| SCHEMBL26946539 | 0.77 | PIM1 (0.38) | AVPR1APIM1BRD4BRPF1MEN1 | |
| SCHEMBL30910112 | 0.76 | EPHX2 (0.55) | AVPR1ABRD4MEN1KMT2AEPHX2 | |
| SCHEMBL6419724 | 0.76 | EPHX2 (0.55) | AVPR1ABRD4MEN1KMT2AEPHX2 | |
| SCHEMBL30910110 | 0.76 | EPHX2 (0.55) | AVPR1ABRD4MEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119612-A | Novel compounds and pharmaceutical compositions comprising the same | 萨皮恩斯生物有限公司 | 2024-05-31 | — | — | CN | disclosed |