⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2656115 | 0.66 | — | — | |
| SCHEMBL7279168 | 0.62 | — | — | |
| SCHEMBL16704009 | 0.59 | — | — | |
| SCHEMBL38918 | 0.52 | — | — | |
| SCHEMBL14616529 | 0.42 | — | — | |
| SCHEMBL18175523 | 0.42 | — | — | |
| SCHEMBL10017669 | 0.38 | — | — | |
| Hydrogen Sulfide SCHEMBL19922257 | 0.35 | — | — | |
| SCHEMBL31175398 | 0.34 | — | — | |
| SCHEMBL25289269 | 0.31 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 861 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024003259-A1 | TEAD INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2024-01-04 | — | — | WO | claimed |
| US-20230416205-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | TENVIE THERAPEUTICS, INC. | 2023-12-28 | — | — | US | claimed |
| US-11814338-B2 | Pyrazolyl and pyrimidinyl tricyclic enones as antioxidant inflammation modulators | REATA PHARMACEUTICALS, INC. (US) | 2023-11-14 | — | — | US | claimed |
| US-20230348516-A1 | YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | MOLECURE S.A. (PL) | 2023-11-02 | — | — | US | claimed |
| EP-4269400-A1 | YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | Molecure SA (PL) | 2023-11-01 | — | — | EP | claimed |
| EP-4247376-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | Denali Therapeutics Inc. (US) | 2023-09-27 | — | — | EP | claimed |
| US-20230295157-A1 | 3-(1H-IMIDAZOL-2-YL)-2,3,8,8A-TETRAHYDROINDOLIZIN-5(1H)-ONE DERIVATIVES USEFUL AS FACTOR XIA INHIBITORS | JANSSEN RESEARCH & DEVELOPMENT, LLC | 2023-09-21 | — | — | US | claimed |
| CN-116507608-A | Compounds, compositions, and methods | 戴纳立制药公司 | 2023-07-28 | — | — | CN | claimed |
| EP-4185588-A1 | 3-(1H-IMIDAZOL-2-YL)-2,3,8,8A-TETRAHYDROINDOLIZIN-5(1H)-ONE DERIVATIVES USEFUL AS FACTOR XIA INHIBITORS | Janssen Pharmaceutica NV (BE) | 2023-05-31 | — | — | EP | claimed |
| CN-116134035-A | 3- (1H-imidazol-2-yl) -2,3,8 a-tetrahydroindol-5 (1H) -one derivatives useful as factor XIA inhibitors | 詹森药业有限公司 | 2023-05-16 | — | — | CN | claimed |
| US-4897476-A | Process for preparing penems | BEECHAM GROUP P.L.C. (GB) | 1990-01-30 | — | — | US | claimed |
| US-4798828-A | LACTAMASE INHIBITORS | BEECHAM GROUP P.L.C. (GB) | 1989-01-17 | — | — | US | claimed |
| EP-0291304-A1 | Process for the conversion of the E-isomer of 6-(substituted methylene)-2-penems into the Z-isomer | BEECHAM GROUP PLC (GB) | 1988-11-17 | — | — | EP | claimed |
| EP-0126012-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING SYMMETRICAL DISULFIDES | SANOFI S.A. (FR) | 1988-01-13 | — | — | EP | claimed |
| EP-0117100-B1 | TRIAZOLE ANTIFUNGAL AGENTS | Pfizer Limited (GB) | 1986-12-10 | — | — | EP | claimed |
| EP-0115400-B1 | TRIAZOLE ANTIFUNGAL AGENTS | Pfizer Limited (GB) | 1986-03-26 | — | — | EP | claimed |
| US-4483863-A | Triazole antifungal agents | PFIZER INC. (US) | 1984-11-20 | — | — | US | claimed |
| EP-0117100-A1 | Triazole antifungal agents | Pfizer Limited (GB) | 1984-08-29 | — | — | EP | claimed |
| EP-0115400-A1 | Triazole antifungal agents | Pfizer Limited (GB) | 1984-08-08 | — | — | EP | claimed |
| US-3998803-A | TEXTILES | FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) | 1976-12-21 | — | — | US | claimed |