SCHEMBL38918

SCHEMBL38918

Cn1n[c]nn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8791559 0.63
SCHEMBL499558 0.61
SCHEMBL7502426 0.60
SCHEMBL8355693 0.60
SCHEMBL2105621 0.55
SCHEMBL309103 0.52
SCHEMBL3171628 0.42
Hydrogen Sulfide SCHEMBL18858709 0.36
SCHEMBL31175398 0.35
SCHEMBL25289269 0.32

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240148732-A1 TRICYCLIC COMPOUNDS USEFUL IN THE TREATMENT OF CANCER, AUTOIMMUNE AND INFLAMMATORY DISORDERS SCHRÖDINGER, INC. 2024-05-09 US claimed
WO-2024013209-A1 PCSK9 INHIBITORS AND METHODS OF USE THEREOF ASTRAZENECA AB (SE) 2024-01-18 WO claimed
US-20240018157-A1 CYCLIC COMPOUNDS AND METHODS OF USING SAME SCHRÖDINGER, INC. 2024-01-18 US claimed
US-11840529-B2 Substituted pyrimidines as LRKK2 inhibitors DENALI THERAPEUTICS INC. (US) 2023-12-12 US claimed
EP-4284804-A1 TRICYCLIC COMPOUNDS USEFUL IN THE TREATMENT OF CANCER, AUTOIMMUNE AND INFLAMMATORY DISORDERS Schrödinger, Inc. (US) 2023-12-06 EP claimed
US-11814338-B2 Pyrazolyl and pyrimidinyl tricyclic enones as antioxidant inflammation modulators REATA PHARMACEUTICALS, INC. (US) 2023-11-14 US claimed
US-20230348516-A1 YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS MOLECURE S.A. (PL) 2023-11-02 US claimed
EP-4269400-A1 YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS Molecure SA (PL) 2023-11-01 EP claimed
US-20230339904-A1 ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS BIOTHERYX, INC. 2023-10-26 US claimed
US-20230278958-A1 TRICYCLIC HETEROCYCLES MERCK PATENT GMBH (DE) 2023-09-07 US claimed
US-4791120-A ANALGESICS THE BOC GROUP, INC. (US) 1988-12-13 US claimed
US-4616007-A PENICILLINS CIBA-GEIGY CORPORATION (US) 1986-10-07 US claimed
EP-0150891-A1 Tricyclic compounds, processes for their preparation, compositions containing such compounds and their use in medicine THE WELLCOME FOUNDATION LIMITED (GB) 1985-08-07 EP claimed
EP-0112283-A1 Heterocyclyl-thio compounds, process for their preparation, pharmaceutical compositions containing them and their use CIBA-GEIGY AG (CH) 1984-06-27 EP claimed
EP-0109362-A1 Hetereocyclic compounds, process for their preparation, pharmaceutical compositions containing them and their use CIBA-GEIGY AG (CH) 1984-05-23 EP claimed
US-4125611-A MICROBIOCIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1978-11-14 US claimed
US-4118566-A Δ2,3 -1,4-Morpholine-2-carboxylic acid derivatives as antibacterial agents BRISTOL-MYERS COMPANY (US) 1978-10-03 US claimed
US-4068080-A BETA-LACTAM ANTIBIOTICS, CEPHALOSPORIN ANALOGS BRISTOL-MYERS COMPANY (US) 1978-01-10 US claimed
US-4061748-A BACTERICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-12-06 US claimed
US-4013648-A BETA-LACTAM ANTIBIOTICS BRISTOL-MYERS COMPANY (US) 1977-03-22 US claimed