Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30910345 | 1.00 | GPR119 (0.36) | GPR119JAK2JAK1TYK2JAK3 | |
| SCHEMBL31049020 | 0.92 | JAK2 (0.33) | GPR119JAK2JAK1TYK2JAK3 | |
| SCHEMBL31049240 | 0.91 | JAK2 (0.33) | GPR119JAK2JAK1TYK2JAK3 | |
| SCHEMBL30149131 | 0.91 | GPR119 (0.36) | GPR119JAK2JAK1TYK2JAK3 | |
| SCHEMBL30149022 | 0.91 | GPR119 (0.36) | GPR119JAK2JAK1TYK2JAK3 | |
| SCHEMBL25437918 | 0.91 | GPR119 (0.36) | GPR119JAK2JAK1TYK2JAK3 | |
| SCHEMBL31048952 | 0.90 | JAK2 (0.32) | GPR119JAK2JAK1TYK2JAK3 | |
| SCHEMBL31712546 | 0.87 | — | — | |
| SCHEMBL31049023 | 0.87 | JAK2 (0.33) | GPR119JAK2JAK1TYK2JAK3 | |
| SCHEMBL31049113 | 0.87 | JAK2 (0.33) | GPR119JAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626895-A1 | 4-(3,8-DIAZABICYCLO[3.2.1]OCTAN-3-YL)-PYRIDO[4,3-D]PYRIMIDINE DERIVATIVES AS INHIBITORS OF THE KRAS(G12D) MUTANT ONCOPROTEIN FOR THE TREATMENT OF CANCER | Ranok Therapeutics (Hangzhou) Co. Ltd. (CN) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024233838-A1 | METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION | RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) | 2024-11-14 | — | — | WO | disclosed |
| WO-2024118926-A1 | 4-(3,8-DIAZABICYCLO[3.2.1]OCTAN-3-YL)-PYRIDO[4,3-D]PYRIMIDINE DERIVATIVES AS INHIBITORS OF THE KRAS(G12D) MUTANT ONCOPROTEIN FOR THE TREATMENT OF CANCER | RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) | 2024-06-06 | — | — | WO | disclosed |