SCHEMBL30910744

SCHEMBL30910744

COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(N)=O)NC(=O)OC(C)(C)C

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CTSL P07711 2/20 0.51
▸ CTSB P07858 1/20 0.51
▸ CTSS P25774 1/20 0.51
▸ CTSK P43235 1/20 0.51
▸ REN P00797 3/20 0.50
▸ BACE1 P56817 8/20 0.48
▸ CAPN1 P07384 1/20 0.46
▸ BIRC2 Q13490 1/20 0.45
▸ FOLH1 Q04609 1/20 0.44
▸ AAK1 Q2M2I8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1026994 0.89 CTSL (0.62) CTSLCTSBCTSSCTSKREN
SCHEMBL1176795 0.89 CTSL (0.62) CTSLCTSBCTSSCTSKREN
SCHEMBL1026997 0.89 CTSL (0.62) CTSLCTSBCTSSCTSKREN
SCHEMBL29480542 0.88 CTSL (0.52) CTSLCTSBCTSSCTSKREN
SCHEMBL21724645 0.88 CTSL (0.55) CTSLCTSBCTSSCTSKREN
SCHEMBL21724644 0.88 CTSL (0.55) CTSLCTSBCTSSCTSKREN
SCHEMBL21737915 0.87 BACE1 (0.48) CTSLCTSBCTSSCTSKREN
SCHEMBL30511412 0.87 BACE1 (0.48) CTSLCTSBCTSSCTSKREN
SCHEMBL30910800 0.87 BACE1 (0.48) CTSLCTSBCTSSCTSKREN
SCHEMBL56907 0.86 CTSL (0.60) CTSLCTSBCTSSCTSKCAPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240398966-A1 CONJUGATES AND METHODS OF USING THE SAME FLAGSHIP PIONEERING INNOVATIONS V INC (US) 2024-12-05 — — US disclosed
US-11998610-B2 Conjugates and methods of using the same FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2024-06-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11998610-B2 Conjugates and methods of using the same CD47, CD44, CD74 CTSL 390/4885CTSB 823/4885CTSS 653/4885
US-20240398966-A1 CONJUGATES AND METHODS OF USING THE SAME CD47, CD44, CD74 CTSL 390/4885CTSB 823/4885CTSS 653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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