Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | XIAP | P98170 | 2/20 | 0.51 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30912021 | 0.90 | MAPT (0.52) | NOTUMMAPTMEN1KMT2AXIAP | |
| SCHEMBL30912000 | 0.85 | NOTUM (0.57) | NOTUMMAPTMEN1KMT2AXIAP | |
| SCHEMBL30911970 | 0.81 | XIAP (0.54) | NOTUMMAPTMEN1KMT2AXIAP | |
| SCHEMBL30911967 | 0.81 | NOTUM (0.50) | NOTUMMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL30911987 | 0.81 | BIRC2 (0.54) | NOTUMMAPTMEN1KMT2ABIRC2 | |
| SCHEMBL30911988 | 0.80 | DRD2 (0.55) | NOTUMMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL30911989 | 0.80 | DRD2 (0.55) | NOTUMMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL30911996 | 0.80 | DRD2 (0.55) | NOTUMMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL30911973 | 0.80 | DRD2 (0.55) | NOTUMMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7339766 | 0.79 | NOTUM (0.83) | NOTUMMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024114782-A1 | SMALL-MOLECULE MODULATORS OF SPIKE PROTEIN | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2024-06-06 | — | — | WO | claimed |
| WO-2024114782-A1 | SMALL-MOLECULE MODULATORS OF SPIKE PROTEIN | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2024-06-06 | — | — | WO | disclosed |