Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | VIPR2 | P41587 | 6/20 | 0.47 |
| ▸ | VIPR1 | P32241 | 4/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | NPY4R | P50391 | 6/20 | 0.46 |
| ▸ | NPY1R | P25929 | 5/20 | 0.46 |
| ▸ | NPY2R | P49146 | 4/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | PTH1R | Q03431 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30912048 | 0.99 | RXFP1 (0.50) | RXFP1VIPR2VIPR1GRIN2DGRIN3B | |
| SCHEMBL30912041 | 0.98 | RXFP1 (0.48) | RXFP1VIPR2VIPR1GRIN2DGRIN3B | |
| SCHEMBL30912043 | 0.95 | RXFP1 (0.49) | RXFP1VIPR2VIPR1GRIN2DGRIN3B | |
| SCHEMBL30912040 | 0.94 | RXFP1 (0.50) | RXFP1VIPR2VIPR1GRIN2DGRIN3B | |
| SCHEMBL30912039 | 0.94 | RXFP1 (0.50) | RXFP1VIPR2VIPR1GRIN2DGRIN3B | |
| SCHEMBL30483984 | 0.94 | RXFP1 (0.46) | RXFP1VIPR2VIPR1NPY4RNPY1R | |
| SCHEMBL30912045 | 0.93 | NPY4R (0.49) | RXFP1VIPR2VIPR1GRIN2DGRIN3B | |
| SCHEMBL30912047 | 0.93 | RXFP1 (0.49) | RXFP1VIPR2VIPR1GRIN2DGRIN3B | |
| SCHEMBL8877920 | 0.89 | GRIN2D (0.51) | RXFP1VIPR2VIPR1GRIN2DGRIN3B | |
| SCHEMBL30879458 | 0.88 | BACE1 (0.47) | RXFP1VIPR2VIPR1NPY4RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240287153-A1 | Treating Inflammatory Lung Disease | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2024-08-29 | — | — | US | disclosed |
| US-11993640-B2 | Treating inflammatory lung disease | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2024-05-28 | — | — | US | disclosed |