Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.54 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.46 |
| ▸ | FPR2 | P25090 | 3/20 | 0.46 |
| ▸ | FPR3 | P25089 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19459113 | 1.00 | RORC (0.54) | RORCUSP30PDE4BFPR2FPR3 | |
| SCHEMBL31341952 | 0.89 | RORC (0.48) | RORCUSP30PDE4BFPR2FPR3 | |
| SCHEMBL27012379 | 0.89 | RORC (0.48) | RORCUSP30PDE4BFPR2FPR3 | |
| SCHEMBL29059260 | 0.89 | RORC (0.48) | RORCUSP30PDE4BFPR2FPR3 | |
| SCHEMBL24494926 | 0.89 | RORC (0.48) | RORCUSP30PDE4BFPR2FPR3 | |
| SCHEMBL24494925 | 0.89 | RORC (0.48) | RORCUSP30PDE4BFPR2FPR3 | |
| SCHEMBL29059278 | 0.89 | RORC (0.48) | RORCUSP30PDE4BFPR2FPR3 | |
| SCHEMBL30912573 | 0.87 | RORC (0.54) | RORCUSP30PDE4BTACR1NAMPT | |
| SCHEMBL20148976 | 0.87 | RORC (0.57) | RORCUSP30PDE4BFPR2FPR3 | |
| SCHEMBL20149241 | 0.87 | RORC (0.57) | RORCUSP30PDE4BFPR2FPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619406-A1 | TRICYCLIC COMPOUNDS | Schrödinger, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107393-A1 | TRICYCLIC COMPOUNDS | SCHRÖDINGER, INC. (US) | 2024-05-23 | — | — | WO | disclosed |