Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1546436 | 0.82 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPTSLC18A3PDE5A | |
| SCHEMBL19803235 | 0.82 | MEN1 (0.43) | ALDH1A1LMNAHTRA1HSD11B1SMN1; SMN2 | |
| SCHEMBL29106585 | 0.79 | MAPT (0.49) | ALDH1A1LMNAMAPTSLC18A3PDE5A | |
| SCHEMBL27480860 | 0.79 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTSLC18A3PDE5A | |
| SCHEMBL1546476 | 0.79 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTPDE5ASMN1; SMN2 | |
| SCHEMBL2433145 | 0.78 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL30912538 | 0.78 | KMT2A (0.51) | ALDH1A1LMNAMAPTSLC18A3PDE5A | |
| SCHEMBL4736392 | 0.78 | MAPT (0.65) | ALDH1A1LMNAMAPTSLC18A3FAAH | |
| SCHEMBL15747865 | 0.77 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPTSLC18A3HSD11B1 | |
| SCHEMBL25279026 | 0.77 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTSLC18A3PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619406-A1 | TRICYCLIC COMPOUNDS | Schrödinger, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107393-A1 | TRICYCLIC COMPOUNDS | SCHRÖDINGER, INC. (US) | 2024-05-23 | — | — | WO | disclosed |