Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29086673 | 1.00 | MTOR (0.49) | MTORFAAHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29086879 | 0.86 | MEN1 (0.48) | MTORFAAHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30642939 | 0.86 | MEN1 (0.48) | MTORFAAHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30912925 | 0.84 | SMN1; SMN2 (0.50) | FAAHNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL29086759 | 0.84 | TP53 (0.60) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL30912965 | 0.84 | EGLN1 (0.51) | NPC1RAB9ASMN1; SMN2LMNADGAT1 | |
| SCHEMBL30912931 | 0.84 | TP53 (0.60) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL29086858 | 0.84 | EGLN1 (0.51) | NPC1RAB9ASMN1; SMN2LMNADGAT1 | |
| SCHEMBL29518293 | 0.83 | FAAH (0.62) | FAAHNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28372959 | 0.83 | FAAH (0.62) | FAAHNPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024109642-A1 | USE OF BENZOAZACYCLIC COMPOUND AS ALLOSTERIC MODULATOR OF β2-ADRENOCEPTOR | 常州大学 | 2024-05-30 | — | — | WO | disclosed |