SCHEMBL30912958

SCHEMBL30912958

O=C(Nc1ccccc1)c1n[nH]c2cc(Br)ccc12

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.77
FLT3 P36888 8/20 0.70
CDK2 P24941 4/20 0.70
CCNA2 P20248 1/20 0.70
CCNA1 P78396 1/20 0.70
MAP4K1 Q92918 1/20 0.56
DYRK1A Q13627 2/20 0.52
CSNK2A1 P68400 6/20 0.52
ADORA3 P0DMS8 1/20 0.50
DYRK3 O43781 1/20 0.50
MAP4K4 O95819 1/20 0.50
CDK1 P06493 1/20 0.50
MARK3 P27448 1/20 0.50
CLK2 P49760 1/20 0.50
GSK3B P49841 1/20 0.50
CSNK1G2 P78368 1/20 0.50
CDK5 Q00535 1/20 0.50
MAP4K2 Q12851 1/20 0.50
PRKAA1 Q13131 1/20 0.50
CAMK2B Q13554 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30912934 0.89 FLT3 (0.70) IDO1FLT3CDK2CCNA2CCNA1
SCHEMBL4509961 0.83 FLT3 (0.78) IDO1FLT3CDK2CCNA2CCNA1
SCHEMBL30398090 0.83 FLT3 (1.00) IDO1FLT3CDK2CCNA2CCNA1
SCHEMBL951125 0.83 FLT3 (1.00) IDO1FLT3CDK2CCNA2CCNA1
SCHEMBL29176630 0.83 FLT3 (0.73) IDO1FLT3CDK2CCNA2CCNA1
SCHEMBL30695136 0.83 FLT3 (0.73) IDO1FLT3CDK2CCNA2CCNA1
SCHEMBL21811353 0.80 IDO1 (0.64) IDO1FLT3CDK2CCNA2CCNA1
SCHEMBL29871192 0.80 IDO1 (0.64) IDO1FLT3CDK2CCNA2CCNA1
SCHEMBL29176619 0.80 FLT3 (0.58) IDO1FLT3CDK2CCNA2CCNA1
SCHEMBL29176611 0.80 FLT3 (0.72) IDO1FLT3CDK2CCNA2CCNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024109642-A1 USE OF BENZOAZACYCLIC COMPOUND AS ALLOSTERIC MODULATOR OF β2-ADRENOCEPTOR 常州大学 2024-05-30 WO disclosed