Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 7/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | SMO | Q99835 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21990627 | 0.84 | MAP4K1 (0.35) | HTR2CSLC6A4HTR2A | |
| SCHEMBL30913157 | 0.84 | MAP4K1 (0.35) | HTR2CSLC6A4HTR2A | |
| SCHEMBL22011646 | 0.84 | MAP4K1 (0.35) | HTR2CSLC6A4HTR2A | |
| SCHEMBL30913139 | 0.84 | AURKA (0.37) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL22012277 | 0.82 | CACNA1G (0.37) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL22012577 | 0.82 | CACNA1G (0.37) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL30500363 | 0.82 | CACNA1G (0.37) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL30136111 | 0.82 | CACNA1G (0.37) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL30913160 | 0.81 | PIK3C3 (0.41) | PIK3CA | |
| SCHEMBL30913137 | 0.81 | MAP4K1 (0.34) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103369-A | Pyridolactam derivatives, preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-05-28 | — | — | CN | disclosed |