Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 12/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29194320 | 1.00 | GAA (0.45) | GAAMAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL30913270 | 0.85 | RAB9A (0.60) | RAB9AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29194323 | 0.85 | RAB9A (0.60) | RAB9AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29194334 | 0.81 | MAPT (0.46) | MAPTRAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL29194326 | 0.80 | RAB9A (0.47) | RAB9AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29194327 | 0.80 | RAB9A (0.47) | RAB9AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29194319 | 0.78 | RAB9A (0.52) | RAB9AALDH1A1KMT2AKDM1AHPGD | |
| SCHEMBL29194318 | 0.75 | RAB9A (0.49) | RAB9AALDH1A1KMT2AKDM1AHPGD | |
| SCHEMBL29194316 | 0.74 | RAB9A (0.48) | RAB9AALDH1A1KMT2AKDM1AHPGD | |
| SCHEMBL29194329 | 0.73 | RAB9A (0.40) | MAPTRAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886750-A | Azaphenanthrene compound with BRD4 protein inhibition effect, and preparation method and application thereof | 山东大学 | 2024-04-16 | — | — | CN | disclosed |