Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 0.84 |
| ▸ | PPARG | P37231 | 15/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | EGFR | P00533 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | DRD1 | P21728 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.62 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.62 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.62 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.62 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.62 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.62 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.62 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.62 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30388705 | 0.92 | RXRA (1.00) | RXRAPPARGCYP1A2MAPTMAPK1 | |
| SCHEMBL17119495 | 0.92 | RXRA (1.00) | RXRAPPARGCYP1A2MAPTMAPK1 | |
| SCHEMBL30913364 | 0.92 | RXRA (0.80) | RXRAPPARGCYP1A2MAPTMAPK1 | |
| SCHEMBL30913483 | 0.90 | PPARG (0.77) | RXRAPPARGCYP1A2MAPTMAPK1 | |
| SCHEMBL24101847 | 0.88 | RXRA (0.88) | RXRAPPARGCYP1A2MAPTMAPK1 | |
| SCHEMBL30913339 | 0.84 | RXRA (0.85) | RXRAPPARGCYP1A2MAPTMAPK1 | |
| SCHEMBL25308793 | 0.84 | RXRA (0.85) | RXRAPPARGCYP1A2MAPTMAPK1 | |
| SCHEMBL12181842 | 0.83 | RXRA (0.83) | RXRAPPARGCYP1A2MAPTMAPK1 | |
| SCHEMBL29068225 | 0.83 | RXRA (0.83) | RXRAPPARGCYP1A2MAPTMAPK1 | |
| SCHEMBL30389912 | 0.83 | RXRA (0.83) | RXRAPPARGCYP1A2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619369-A1 | INDENE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | Nucmito Pharmaceuticals Co., Ltd. (CN) | 2025-09-24 | — | — | EP | claimed |
| WO-2024104384-A1 | INDENE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | NUCMITO PHARMACEUTICALS CO. LTD. (CN) | 2024-05-23 | — | — | WO | claimed |
| EP-4619369-A1 | INDENE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | Nucmito Pharmaceuticals Co., Ltd. (CN) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024104384-A1 | INDENE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | NUCMITO PHARMACEUTICALS CO. LTD. (CN) | 2024-05-23 | — | — | WO | disclosed |