Azd-8797

Azd-8797

SCHEMBL30914151

CC(C)CC(CO)Nc1nc(S[C@@H](C)c2ccccc2)nc2nc(N)sc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CX3CR1 P49238 20/20 1.00
CXCR2 P25025 18/20 1.00
ADORA1 P30542 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Azd-8797 SCHEMBL29473543 1.00 CX3CR1 (1.00) CX3CR1CXCR2ADORA1
Azd-8797 SCHEMBL30914115 1.00 CX3CR1 (1.00) CX3CR1CXCR2ADORA1
Azd-8797 SCHEMBL213194 1.00 CX3CR1 (1.00) CX3CR1CXCR2ADORA1
Azd-8797 SCHEMBL212862 1.00 CX3CR1 (1.00) CX3CR1CXCR2ADORA1
Azd-8797 SCHEMBL212398 1.00 CX3CR1 (1.00) CX3CR1CXCR2ADORA1
Azd-8797 SCHEMBL23528828 1.00 CX3CR1 (1.00) CX3CR1CXCR2ADORA1
Azd-8797 SCHEMBL31643602 1.00 CX3CR1 (1.00) CX3CR1CXCR2ADORA1
Azd-8797 SCHEMBL23828002 0.99 CX3CR1 (0.98) CX3CR1CXCR2ADORA1
Azd-8797 SCHEMBL23828005 0.99 CX3CR1 (0.98) CX3CR1CXCR2ADORA1
Azd-8797 SCHEMBL30288320 0.99 CX3CR1 (0.98) CX3CR1CXCR2ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112218853-B Process for the stereoselective preparation of chiral 2- [ (hetero) aralkylthio ] pyrimidines and products obtainable therefrom 坎塞拉有限公司 2024-07-02 CN claimed
CN-112218853-B Process for the stereoselective preparation of chiral 2- [ (hetero) aralkylthio ] pyrimidines and products obtainable therefrom 坎塞拉有限公司 2024-07-02 CN disclosed