Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.47 |
| ▸ | CTSS | P25774 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26911150 | 1.00 | CTSK (0.47) | CTSKCTSSPPARAPPARGMEN1 | |
| SCHEMBL26911147 | 1.00 | CTSK (0.47) | CTSKCTSSPPARAPPARGMEN1 | |
| SCHEMBL15239813 | 0.92 | CTSK (0.48) | CTSKCTSSPPARAPPARGMEN1 | |
| SCHEMBL30916094 | 0.92 | CTSK (0.48) | CTSKCTSSPPARAPPARGMEN1 | |
| SCHEMBL14533577 | 0.92 | CTSK (0.48) | CTSKCTSSPPARAPPARGMEN1 | |
| SCHEMBL27041613 | 0.90 | CTSK (0.47) | CTSKCTSSPPARAPPARGMEN1 | |
| SCHEMBL27041611 | 0.90 | CTSK (0.47) | CTSKCTSSPPARAPPARGMEN1 | |
| SCHEMBL26822676 | 0.88 | CTSK (0.50) | CTSKCTSSPPARAPPARGMEN1 | |
| SCHEMBL31407478 | 0.88 | CTSK (0.50) | CTSKCTSSPPARAPPARGMEN1 | |
| SCHEMBL2703149 | 0.88 | CTSK (0.50) | CTSKCTSSPPARAPPARGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587443-A1 | MACROCYCLIC CFTR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2025-07-23 | — | — | EP | disclosed |
| WO-2025043094-A1 | BENZOTHIA(DIA)ZEPINE COMPOUNDS FOR TREATMENT OF HBV AND HDV | ASSEMBLY BIOSCIENCES, INC. (US) | 2025-02-27 | — | — | WO | disclosed |
| WO-2024177984-A1 | BENZOTHIA(DIA)ZEPINE COMPOUNDS FOR TREATMENT OF HBV AND HDV | ASSEMBLY BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |
| WO-2024056798-A1 | MACROCYCLIC CFTR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-03-21 | — | — | WO | disclosed |