Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.41 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3091675 | 1.00 | OTC (0.41) | OTCC3AR1CA12CA1CA2 | |
| SCHEMBL3103112 | 0.95 | OTC (0.37) | OTCCA12CA1CA2CA9 | |
| SCHEMBL2985623 | 0.89 | OTC (0.43) | OTCC3AR1CA12CA1CA2 | |
| SCHEMBL2985627 | 0.89 | OTC (0.43) | OTCC3AR1CA12CA1CA2 | |
| SCHEMBL3109250 | 0.88 | OTC (0.39) | OTCCA12CA1CA2CA9 | |
| SCHEMBL3109225 | 0.88 | OTC (0.39) | OTCCA12CA1CA2CA9 | |
| SCHEMBL3087403 | 0.86 | OTC (0.40) | OTCCA12CA1CA2CA9 | |
| SCHEMBL2979471 | 0.85 | OTC (0.39) | OTCC3AR1CA12CA1CA2 | |
| SCHEMBL3086310 | 0.84 | OTC (0.35) | OTCCA12CA1CA2CA9 | |
| SCHEMBL3090812 | 0.80 | LMNA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |