⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL510744 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28013142 | 0.98 | UHRF1 (0.48) | — | |
| Bromide SCHEMBL30220675 | 0.98 | UHRF1 (0.48) | — | |
| Hydrochloric Acid SCHEMBL1193641 | 0.98 | UHRF1 (0.48) | — | |
| SCHEMBL30932457 | 0.81 | UHRF1 (0.54) | — | |
| SCHEMBL12596 | 0.79 | — | — | |
| SCHEMBL31421768 | 0.79 | — | — | |
| SCHEMBL8569698 | 0.78 | UHRF1 (0.42) | — | |
| SCHEMBL1443623 | 0.77 | — | — | |
| SCHEMBL22685043 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |
| CN-118159530-A | Compounds for the treatment of pain, in particular neuropathic pain and/or other diseases or disorders associated with AT2R and/or AT2R mediated signalling | 康福治疗有限公司 | 2024-06-07 | — | — | CN | disclosed |