Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | OTC | P00480 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3100823 | 0.95 | OTC (0.39) | CA12CA1CA2CA9OTC | |
| SCHEMBL3100850 | 0.95 | OTC (0.39) | CA12CA1CA2CA9OTC | |
| SCHEMBL27764519 | 0.89 | C3AR1 (0.41) | CA12CA1CA2CA9OTC | |
| SCHEMBL2989505 | 0.89 | C3AR1 (0.41) | CA12CA1CA2CA9OTC | |
| SCHEMBL3097987 | 0.88 | ALOX15 (0.36) | CA12CA1CA2CA9OTC | |
| SCHEMBL3109216 | 0.86 | ANPEP (0.34) | — | |
| SCHEMBL2989750 | 0.84 | C3AR1 (0.45) | OTCFNTAFNTBC3AR1FOLH1 | |
| SCHEMBL2989744 | 0.84 | C3AR1 (0.45) | OTCFNTAFNTBC3AR1FOLH1 | |
| SCHEMBL2992625 | 0.83 | OTC (0.37) | CA12CA1CA2CA9OTC | |
| SCHEMBL3091575 | 0.83 | OTC (0.37) | CA12CA1CA2CA9OTC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |