Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.51 |
| ▸ | RECQL | P46063 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | BLM | P54132 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | APEX1 | P27695 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29196545 | 1.00 | TDP1 (0.51) | TDP1RECQLKDM4EMAPTBLM | |
| SCHEMBL29196543 | 0.94 | TDP1 (0.49) | TDP1RECQLKDM4EMAPTBLM | |
| SCHEMBL30918750 | 0.94 | TDP1 (0.49) | TDP1RECQLKDM4EMAPTBLM | |
| SCHEMBL30918749 | 0.90 | TDP1 (0.55) | TDP1RECQLKDM4EMAPTBLM | |
| SCHEMBL29196541 | 0.90 | TDP1 (0.55) | TDP1RECQLKDM4EMAPTBLM | |
| SCHEMBL29196542 | 0.82 | TDP1 (0.58) | TDP1RECQLKDM4EMAPTBLM | |
| SCHEMBL30918751 | 0.82 | TDP1 (0.58) | TDP1RECQLKDM4EMAPTBLM | |
| SCHEMBL1964126 | 0.81 | TDP1 (0.42) | TDP1RECQLKDM4EMAPTBLM | |
| SCHEMBL10739744 | 0.81 | TDP1 (0.56) | TDP1RECQLKDM4EMAPTBLM | |
| SCHEMBL5323563 | 0.81 | ESR1 (0.51) | TDP1KDM4EMAPTLMNAAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903072-A | Dopa compound and preparation method and application thereof | 深圳市松柏科工股份有限公司 | 2024-04-19 | — | — | CN | disclosed |