Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 8/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30918981 | 0.89 | MPO (0.41) | MPOESR2NPC1RAB9ANR1H2 | |
| SCHEMBL17642774 | 0.89 | MPO (0.41) | MPOESR2NPC1RAB9ANR1H2 | |
| SCHEMBL24908851 | 0.87 | MPO (0.39) | MPOESR2NPC1RAB9ANR1H2 | |
| SCHEMBL19953719 | 0.87 | MPO (0.39) | MPOESR2NPC1RAB9ANR1H2 | |
| SCHEMBL30474562 | 0.87 | MPO (0.40) | MPOESR2NPC1RAB9ANR1H2 | |
| SCHEMBL4523127 | 0.87 | MPO (0.40) | MPOESR2NPC1RAB9ANR1H2 | |
| SCHEMBL861986 | 0.87 | MPO (0.40) | MPOESR2NPC1RAB9ANR1H2 | |
| SCHEMBL1840941 | 0.86 | MPO (0.39) | MPOESR2NPC1RAB9ANR1H2 | |
| SCHEMBL21328581 | 0.86 | MPO (0.39) | MPOESR2NPC1RAB9ANR1H2 | |
| SCHEMBL17970755 | 0.86 | MPO (0.39) | MPOESR2NPC1RAB9ANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903171-A | Integrin inhibitors of a class of bicyclic derivatives | 上海如凌生物医药有限公司 | 2024-04-19 | — | — | CN | disclosed |