Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24896788 | 1.00 | NAMPT (0.41) | NAMPTPTGDR2BCL2HDAC3HDAC8 | |
| SCHEMBL25255538 | 0.87 | NAMPT (0.39) | NAMPTPTGDR2BCL2HDAC3HDAC8 | |
| SCHEMBL25253508 | 0.86 | MAPKAPK2 (0.41) | NAMPTPTGDR2BCL2HDAC3HDAC8 | |
| SCHEMBL25255285 | 0.85 | AR (0.41) | NAMPTPTGDR2BCL2HDAC3HDAC8 | |
| SCHEMBL25413782 | 0.84 | MAPT (0.38) | KDM4EMAPT | |
| SCHEMBL26453252 | 0.79 | PTGDR2 (0.36) | NAMPTPTGDR2MAPKAPK2BRD4RORC | |
| SCHEMBL30362248 | 0.79 | PTGDR2 (0.38) | NAMPTPTGDR2HDAC3HDAC8NCOR2 | |
| SCHEMBL25251320 | 0.79 | PTGDR2 (0.38) | NAMPTPTGDR2HDAC3HDAC8NCOR2 | |
| SCHEMBL24896789 | 0.79 | PTGDR2 (0.36) | NAMPTPTGDR2MAPKAPK2CYP17A1BRD4 | |
| SCHEMBL30919455 | 0.79 | PTGDR2 (0.36) | NAMPTPTGDR2MAPKAPK2CYP17A1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119609-A | Imidazole derivatives and their use as antibiotics | 豪夫迈·罗氏有限公司 | 2024-05-31 | — | — | CN | disclosed |