Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | GALR3 | O60755 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25170637 | 0.91 | MAPT (0.74) | MAPTALDH1A1LMNAGALR3TDP1 | |
| SCHEMBL30919728 | 0.86 | CHRM4 (0.45) | MAPT | |
| SCHEMBL21786064 | 0.85 | MAPT (0.75) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL31334687 | 0.85 | MAPT (0.53) | MAPTALDH1A1LMNASIGMAR1TDP1 | |
| SCHEMBL26495684 | 0.85 | ALDH1A1 (0.52) | MAPTALDH1A1LMNATDP1POLB | |
| SCHEMBL30497535 | 0.85 | ALDH1A1 (0.52) | MAPTALDH1A1LMNATDP1POLB | |
| SCHEMBL4516920 | 0.83 | MAPT (0.56) | MAPTALDH1A1LMNAGALR3SMN1; SMN2 | |
| SCHEMBL29986651 | 0.83 | MAPT (0.75) | MAPTALDH1A1LMNASMN1; SMN2POLB | |
| SCHEMBL25584267 | 0.82 | MAPT (0.71) | MAPTALDH1A1LMNAGALR3TDP1 | |
| SCHEMBL30985158 | 0.81 | MAPT (0.65) | MAPTALDH1A1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618755-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107746-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES (US) | 2024-05-23 | — | — | WO | disclosed |