Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30919856 | 0.82 | CCNE2 (0.41) | NPC1KDM4ELRRK2TP53HCRTR2 | |
| SCHEMBL30919913 | 0.82 | SMN1; SMN2 (0.36) | NPC1KDM4EATMMAPTHCRTR2 | |
| SCHEMBL30919727 | 0.82 | SMN1; SMN2 (0.36) | MAPTHCRTR2SMN1; SMN2 | |
| SCHEMBL30919792 | 0.82 | CCNE2 (0.41) | NPC1KDM4ELRRK2TP53HCRTR2 | |
| SCHEMBL30919906 | 0.82 | CCNE2 (0.41) | NPC1KDM4ELRRK2TP53HCRTR2 | |
| SCHEMBL30919604 | 0.82 | SMN1; SMN2 (0.36) | MAPTHCRTR2SMN1; SMN2 | |
| SCHEMBL30919741 | 0.81 | HCRTR2 (0.47) | MAPTTP53HCRTR2SMN1; SMN2 | |
| SCHEMBL30919884 | 0.81 | SMN1; SMN2 (0.41) | NPC1KDM4EMAPTRAB9ALRRK2 | |
| SCHEMBL30919519 | 0.79 | MAP4K4 (0.43) | MAPTLRRK2HCRTR2MAP4K4SMN1; SMN2 | |
| SCHEMBL1935622 | 0.79 | SMN1; SMN2 (0.49) | KDM4EMAPTHCRTR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618755-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107746-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES (US) | 2024-05-23 | — | — | WO | disclosed |