Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMPD3 | Q9NY59 | 4/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30919856 | 1.00 | CCNE2 (0.41) | CCNE2CCNE1CDK2MAPK13MAPK12 | |
| SCHEMBL30919792 | 1.00 | CCNE2 (0.41) | CCNE2CCNE1CDK2MAPK13MAPK12 | |
| SCHEMBL31262462 | 0.86 | MAPK13 (0.41) | CCNE2CCNE1CDK2MAPK13MAPK12 | |
| SCHEMBL30919913 | 0.82 | SMN1; SMN2 (0.36) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL30919727 | 0.82 | SMN1; SMN2 (0.36) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL30919945 | 0.82 | NPC1 (0.46) | LRRK2KDM4EHCRTR2NPC1TP53 | |
| SCHEMBL30919604 | 0.82 | SMN1; SMN2 (0.36) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL15022112 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EHCRTR2MEN1KMT2A | |
| SCHEMBL30919519 | 0.79 | MAP4K4 (0.43) | LRRK2GAAHCRTR2MEN1KMT2A | |
| SCHEMBL1935226 | 0.79 | SMN1; SMN2 (0.49) | ALDH1A1HCRTR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618755-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107746-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES (US) | 2024-05-23 | — | — | WO | disclosed |