Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 16/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24031472 | 1.00 | GHSR (0.53) | GHSRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL30920110 | 0.91 | GHSR (0.47) | GHSR | |
| SCHEMBL24031026 | 0.91 | GHSR (0.47) | GHSR | |
| SCHEMBL25895663 | 0.87 | GHSR (0.46) | GHSRLMNA | |
| SCHEMBL2081445 | 0.86 | ESR2 (0.49) | GHSR | |
| SCHEMBL29233309 | 0.86 | GHSR (0.55) | GHSRGPR119 | |
| SCHEMBL30439807 | 0.86 | GHSR (0.49) | GHSR | |
| SCHEMBL17391179 | 0.84 | GHSR (0.46) | GHSR | |
| SCHEMBL17391103 | 0.84 | GHSR (0.57) | GHSRKDM4ELMNA | |
| SCHEMBL17391030 | 0.84 | GHSR (0.54) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118580188-A | Can be used as ROR gamma regulator aniline compound (B) | 励缔(杭州)医药科技有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-113666863-B | Biaryl compounds useful as rory modulators | 励缔(杭州)医药科技有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-113773251-B | Anilines useful as rory modulators | 励缔(杭州)医药科技有限公司 | 2024-06-11 | — | — | CN | disclosed |