Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | DAO | P14920 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.59 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.58 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.55 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1647680 | 1.00 | KDM4E (0.59) | KDM4EHPGDHSD17B10MAPTDAO | |
| Hydrochloric Acid SCHEMBL28903044 | 0.98 | KDM4E (0.58) | KDM4EHPGDHSD17B10MAPTDAO | |
| SCHEMBL378196 | 0.85 | SMAD3 (0.66) | KDM4EHPGDHSD17B10MAPTDAO | |
| Hydrochloric Acid SCHEMBL6919627 | 0.84 | SMAD3 (0.64) | KDM4EHPGDHSD17B10MAPTDAO | |
| SCHEMBL20267033 | 0.84 | HRH4 (0.55) | HRH4 | |
| SCHEMBL8889640 | 0.84 | HRH4 (0.55) | HRH4 | |
| SCHEMBL2730304 | 0.84 | HRH4 (0.58) | EIF4A3HRH4 | |
| SCHEMBL20612113 | 0.81 | HRH4 (0.49) | EIF4A3HRH4 | |
| SCHEMBL22152424 | 0.80 | HRH4 (0.55) | HRH4ALDH1A1LMNA | |
| SCHEMBL20535295 | 0.80 | ALOX15 (0.68) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4601635-A2 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | Maze Therapeutics, Inc. (US) | 2025-08-20 | — | — | EP | disclosed |