Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | GPR183 | P32249 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1647680 | 0.80 | KDM4E (0.59) | HRH4 | |
| SCHEMBL30920180 | 0.80 | KDM4E (0.59) | HRH4 | |
| SCHEMBL20267033 | 0.78 | HRH4 (0.55) | HRH4DRD4GPR183FLT3 | |
| Hydrochloric Acid SCHEMBL28903044 | 0.78 | KDM4E (0.58) | HRH4 | |
| SCHEMBL2730304 | 0.78 | HRH4 (0.58) | HRH4DRD4GPR183FLT3 | |
| SCHEMBL8889640 | 0.78 | HRH4 (0.55) | HRH4DRD4GPR183FLT3 | |
| SCHEMBL12786510 | 0.76 | HRH4 (0.55) | HRH4 | |
| SCHEMBL20535295 | 0.74 | ALOX15 (0.68) | HRH4DRD4 | |
| SCHEMBL22152424 | 0.74 | HRH4 (0.55) | HRH4DRD4 | |
| SCHEMBL19966319 | 0.74 | HRH4 (0.55) | HRH4DRD4GPR183FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2892880-B1 | INDOLE CARBOXAMIDE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2017-11-22 | — | — | EP | disclosed |