Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 4/20 | 0.42 |
| ▸ | RPS6KA2 | Q15349 | 10/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3087058 | 0.91 | RPS6KA2 (0.41) | RPS6KA3RPS6KA2SIGMAR1ALDH1A1CYP1A2 | |
| SCHEMBL50820 | 0.80 | RPS6KA3 (0.49) | RPS6KA3RPS6KA2ALDH1A1MEN1KMT2A | |
| SCHEMBL3085393 | 0.74 | PARP1 (0.45) | RPS6KA3RPS6KA2SIGMAR1ALDH1A1 | |
| SCHEMBL3088133 | 0.73 | RPS6KA3 (0.54) | RPS6KA3RPS6KA2HTR2A | |
| Trifluoroacetic Acid SCHEMBL4153237 | 0.71 | PRKCA (0.39) | — | |
| Trifluoroacetic Acid SCHEMBL4153234 | 0.71 | PRKCA (0.39) | — | |
| SCHEMBL896122 | 0.69 | PRKCA (0.57) | SIGMAR1 | |
| SCHEMBL896350 | 0.69 | PRKCA (0.58) | ALDH1A1KMT2A | |
| SCHEMBL4831402 | 0.69 | RPS6KA3 (0.59) | RPS6KA3RPS6KA2 | |
| Hydrochloric Acid SCHEMBL3085990 | 0.68 | PRKCA (0.57) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795247-B2 | Tetracyclic indole derivatives as antiviral agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2010-09-14 | — | — | US | disclosed |
| US-20060100262-A1 | Tetracyclic indole derivatives as antiviral agents | ISTITUTO DI RICHERCHEDI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IRMB) (IT) | 2006-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100262-A1 | Tetracyclic indole derivatives as antiviral agents | IDO1, ZC3HAV1, IDO2 | RPS6KA3 1950/4885RPS6KA2 2765/4885HTR1A 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.