SCHEMBL30922326

SCHEMBL30922326

O=C1CCC(c2coc3cc(C4CCN(Cc5ccccc5)CC4)ccc23)C(=O)N1

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 3/20 0.46
CRBN Q96SW2 3/20 0.46
IKZF2 Q9UKS7 5/20 0.43
IKZF1 Q13422 3/20 0.42
DRD2 P14416 2/20 0.42
ACHE P22303 2/20 0.42
PARP1 P09874 3/20 0.41
MAOB P27338 2/20 0.41
BCHE P06276 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30922283 0.80 IKZF1 (0.55) DDB1CRBNIKZF2IKZF1DRD2
SCHEMBL23117767 0.76 CRBN (0.55) DDB1CRBNIKZF1PARP1
SCHEMBL23115246 0.75 CRBN (0.46) DDB1CRBN
SCHEMBL31426245 0.74 DDB1 (0.58) DDB1CRBN
SCHEMBL23115216 0.74 DDB1 (0.58) DDB1CRBN
SCHEMBL23115214 0.74 DDB1 (0.58) DDB1CRBN
SCHEMBL23115215 0.74 DDB1 (0.58) DDB1CRBN
SCHEMBL31454804 0.74 IKZF2 (0.51) DDB1CRBNIKZF2IKZF1DRD2
SCHEMBL24938771 0.73 CRBN (0.44) DDB1CRBN
SCHEMBL24950299 0.73 CRBN (0.47) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035361-A1 COMPOUNDS FOR MODULATING HUR (ELAVL1) SHANGHAI DEGRON BIOMEDICAL TECH CO LTD (CN) 2026-02-05 US disclosed
EP-4626880-A1 COMPOUNDS FOR MODULATING HUR (ELAVL1) Shanghai Degron Biomedical Technology Co., Ltd. (CN) 2025-10-08 EP disclosed
WO-2024114639-A1 COMPOUNDS FOR MODULATING HUR (ELAVL1) SHANGHAI DEGRON BIOMEDICAL TECHNOLOGY CO., LTD. (CN) 2024-06-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035361-A1 COMPOUNDS FOR MODULATING HUR (ELAVL1) ELAVL1, ELAVL3, HNRNPL DDB1 568/4885CRBN 1001/4885IKZF2 2095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.