Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | INSR | P06213 | 1/20 | 0.58 |
| ▸ | NPM1 | P06748 | 1/20 | 0.58 |
| ▸ | IGF1R | P08069 | 1/20 | 0.58 |
| ▸ | BCR | P11274 | 1/20 | 0.58 |
| ▸ | FLT3 | P36888 | 1/20 | 0.58 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.58 |
| ▸ | TYK2 | P29597 | 1/20 | 0.56 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.56 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | JAK1 | P23458 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31005758 | 0.86 | TYK2 (0.57) | EGFRRAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL30923880 | 0.80 | EGFR (0.77) | EGFRRAB9ANPC1JAK2JAK1 | |
| SCHEMBL10063188 | 0.78 | ITK (0.81) | EGFRRAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL31005759 | 0.77 | RAB9A (0.63) | EGFRRAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL1663240 | 0.77 | KMT2A (0.49) | RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3368022 | 0.75 | TYK2 (0.70) | RAB9ANPC1TYK2 | |
| SCHEMBL1161155 | 0.74 | TYK2 (0.69) | RAB9ANPC1TYK2 | |
| SCHEMBL30923740 | 0.74 | EGFR (0.75) | EGFRJAK2JAK1 | |
| SCHEMBL21938137 | 0.73 | TYK2 (0.68) | RAB9ANPC1TYK2 | |
| Hydrochloric Acid SCHEMBL2591261 | 0.73 | TYK2 (0.68) | RAB9ANPC1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105364-A1 | HETEROCYCLIC INHIBITORS OF CDC-LIKE KINASES | CURADEV PHARMA LTD (GB) | 2024-05-23 | — | — | WO | disclosed |