Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.70 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.54 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.50 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.50 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.50 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.50 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.50 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.50 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30924138 | 1.00 | EPHX2 (0.70) | EPHX2ACKR3KCNH2MCHR1CACNA1G | |
| SCHEMBL30924062 | 0.91 | EPHX2 (0.70) | EPHX2CACNA1GACHE | |
| SCHEMBL30924058 | 0.90 | EPHX2 (0.69) | EPHX2ACKR3CACNA1GACHEPRKAB2 | |
| SCHEMBL30924107 | 0.89 | ERCC1 (0.60) | EPHX2ACKR3KCNH2MCHR1CACNA1G | |
| SCHEMBL30924072 | 0.88 | EPHX2 (0.67) | EPHX2ACKR3CACNA1GACHEPRKAB2 | |
| SCHEMBL30924112 | 0.88 | EPHX2 (0.77) | EPHX2ACHE | |
| SCHEMBL30924032 | 0.88 | ACKR3 (0.61) | EPHX2ACKR3KCNH2MCHR1MEN1 | |
| SCHEMBL30924024 | 0.87 | ACKR3 (0.55) | EPHX2ACKR3KCNH2MCHR1CACNA1G | |
| SCHEMBL30924061 | 0.83 | KCNH2 (0.54) | EPHX2ACKR3KCNH2MCHR1 | |
| SCHEMBL20589000 | 0.82 | EPHX2 (1.00) | EPHX2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618985-A1 | DUAL INHIBITORS OF SIGMA-1 RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE AND THEIR USE IN THE TREATMENT OF PAIN | Universitat De Barcelona (ES) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024105234-A1 | DUAL INHIBITORS OF SIGMA-1 RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE AND THEIR USE IN THE TREATMENT OF PAIN | UNIVERSITAT DE BARCELONA (ES) | 2024-05-23 | — | — | WO | disclosed |