Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 3/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.55 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.52 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30923923 | 0.94 | EPHX2 (0.60) | ACKR3EPHX2CACNA1GPTBP1MEN1 | |
| SCHEMBL30924127 | 0.90 | EPHX2 (0.58) | ACKR3EPHX2CACNA1GPTBP1CHRM4 | |
| SCHEMBL30924082 | 0.90 | ERCC1 (0.57) | ACKR3EPHX2CACNA1GPTBP1MEN1 | |
| SCHEMBL30924025 | 0.89 | CACNA1G (0.59) | EPHX2CACNA1GPTBP1MEN1KMT2A | |
| SCHEMBL30924123 | 0.89 | CHRM2 (0.59) | ACKR3CHRM4KCNH2MCHR1CHRM2 | |
| SCHEMBL30924109 | 0.89 | CHRM2 (0.53) | ACKR3EPHX2CACNA1GPTBP1CHRM4 | |
| SCHEMBL30924054 | 0.89 | EPHX2 (0.57) | EPHX2CACNA1GPTBP1MEN1KMT2A | |
| SCHEMBL30924111 | 0.88 | CHRM4 (0.61) | EPHX2PTBP1CHRM4ACHECHRM2 | |
| SCHEMBL30924137 | 0.87 | EPHX2 (0.70) | ACKR3EPHX2CACNA1GMEN1KMT2A | |
| SCHEMBL30924138 | 0.87 | EPHX2 (0.70) | ACKR3EPHX2CACNA1GMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618985-A1 | DUAL INHIBITORS OF SIGMA-1 RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE AND THEIR USE IN THE TREATMENT OF PAIN | Universitat De Barcelona (ES) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024105234-A1 | DUAL INHIBITORS OF SIGMA-1 RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE AND THEIR USE IN THE TREATMENT OF PAIN | UNIVERSITAT DE BARCELONA (ES) | 2024-05-23 | — | — | WO | disclosed |