Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 14/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 14/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 14/20 | 0.46 |
| ▸ | PLG | P00747 | 10/20 | 0.46 |
| ▸ | F2 | P00734 | 4/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.42 |
| ▸ | CCNK | O75909 | 1/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27229621 | 1.00 | F10 (0.46) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL27229637 | 0.94 | F10 (0.42) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL30924639 | 0.94 | F10 (0.42) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL27229583 | 0.90 | F10 (0.46) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL30924653 | 0.90 | F10 (0.46) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL30924665 | 0.89 | F10 (0.46) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL27229561 | 0.89 | F10 (0.46) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL30924580 | 0.89 | RYR2 (0.43) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL27229623 | 0.89 | RYR2 (0.43) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL30924581 | 0.88 | F10 (0.45) | F10PRSS1PRSS2PRSS3PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174659-A1 | COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR | Opna Bio SA (CH) | 2024-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174659-A1 | COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR | YAP1, YES1, LATS1 | F10 4241/4885PRSS1 3215/4885PRSS2 3960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.