SCHEMBL30924748

SCHEMBL30924748

CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CS)NC(=O)[C@H](C)N)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 1/20 0.52
▸ NPY1R P25929 1/20 0.51
▸ NPY2R P49146 1/20 0.51
▸ NPY4R P50391 1/20 0.51
▸ KISS1R Q969F8 14/20 0.51
▸ BACE1 P56817 1/20 0.48
▸ OPRD1 P41143 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32665677 0.92 TFPI (0.53) TFPINPY1RNPY2RNPY4RKISS1R
SCHEMBL30924727 0.92 TFPI (0.54) TFPINPY1RNPY2RNPY4RKISS1R
SCHEMBL30924753 0.90 NPY4R (0.57) TFPINPY1RNPY2RNPY4RKISS1R
SCHEMBL30924750 0.89 TFPI (0.60) TFPINPY1RNPY2RNPY4RKISS1R
SCHEMBL29971465 0.88 NPY1R (0.56) TFPINPY1RNPY2RNPY4RKISS1R
SCHEMBL30924735 0.88 TFPI (0.59) TFPINPY1RNPY2RNPY4RKISS1R
SCHEMBL30038639 0.87 KISS1R (0.60) TFPINPY1RNPY2RNPY4RKISS1R
SCHEMBL30880909 0.85 KISS1R (0.60) KISS1ROPRD1
SCHEMBL7753372 0.85 BACE1 (0.55) TFPINPY1RNPY2RNPY4RKISS1R
SCHEMBL30617733 0.85 NPY4R (0.56) TFPINPY1RNPY2RNPY4RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250026787-A1 PEPTIDES AND METHODS FOR REDUCING SKIN PIGMENTATION GLO PHARMA, INC. 2025-01-23 — — US disclosed
US-12162956-B2 Peptides and methods for reducing skin pigmentation GLO PHARMA, INC. (US) 2024-12-10 — — US disclosed
US-20240190917-A1 PEPTIDES AND METHODS FOR REDUCING SKIN PIGMENTATION GLO PHARMA, INC. 2024-06-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240190917-A1 PEPTIDES AND METHODS FOR REDUCING SKIN PIGMENTATION MC1R, TYR, MC5R TFPI 918/4885NPY1R 29/4885NPY2R 44/4885
US-12162956-B2 Peptides and methods for reducing skin pigmentation MC1R, TYR, MC5R TFPI 918/4885NPY1R 29/4885NPY2R 44/4885
US-20250026787-A1 PEPTIDES AND METHODS FOR REDUCING SKIN PIGMENTATION MC1R, TYR, MC5R TFPI 918/4885NPY1R 29/4885NPY2R 44/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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