Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.64 |
| ▸ | NPC1 | O15118 | 9/20 | 0.64 |
| ▸ | RAB9A | P51151 | 9/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | ALPL | P05186 | 2/20 | 0.63 |
| ▸ | CDK2 | P24941 | 2/20 | 0.60 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.60 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.60 |
| ▸ | ATG4B | Q9Y4P1 | 4/20 | 0.59 |
| ▸ | GSK3A | P49840 | 1/20 | 0.59 |
| ▸ | GSK3B | P49841 | 1/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.59 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.59 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.59 |
| ▸ | NSD2 | O96028 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067199 | 0.82 | ALPL (0.85) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL18541910 | 0.81 | MEN1 (0.65) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL29057112 | 0.80 | MEN1 (0.64) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL19435594 | 0.80 | MEN1 (0.54) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL28654059 | 0.80 | MEN1 (0.54) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL19435593 | 0.80 | MEN1 (0.54) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL1804666 | 0.80 | NPC1 (0.76) | MEN1KMT2ANPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL28870853 | 0.79 | MEN1 (0.53) | MEN1KMT2ANPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL28870854 | 0.79 | MEN1 (0.53) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL376089 | 0.78 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118978524-A | Nitrazonit derivative and medical application thereof | 绍兴君科臻元医药科技有限公司 | 2024-11-19 | — | — | CN | disclosed |
| CN-112480104-B | Nitrazonit derivative and medical application thereof | 绍兴君科臻元医药科技有限公司 | 2024-06-18 | — | — | CN | disclosed |