Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 20/20 | 1.00 |
| ▸ | JAK2 | O60674 | 1/20 | 1.00 |
| ▸ | EGFR | P00533 | 1/20 | 1.00 |
| ▸ | JAK1 | P23458 | 1/20 | 1.00 |
| ▸ | TTK | P33981 | 1/20 | 1.00 |
| ▸ | FLT3 | P36888 | 1/20 | 1.00 |
| ▸ | TXK | P42681 | 1/20 | 1.00 |
| ▸ | BLK | P51451 | 1/20 | 1.00 |
| ▸ | BTK | Q06187 | 1/20 | 1.00 |
| ▸ | ITK | Q08881 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17202389 | 1.00 | JAK3 (1.00) | JAK3JAK2EGFRJAK1TTK | |
| SCHEMBL30225760 | 1.00 | JAK3 (1.00) | JAK3JAK2EGFRJAK1TTK | |
| SCHEMBL17209829 | 0.94 | JAK3 (1.00) | JAK3JAK2EGFRJAK1TTK | |
| SCHEMBL17209789 | 0.93 | JAK3 (1.00) | JAK3JAK2EGFRJAK1TTK | |
| SCHEMBL17209883 | 0.92 | JAK3 (1.00) | JAK3JAK2EGFRJAK1TTK | |
| SCHEMBL17209823 | 0.92 | JAK3 (1.00) | JAK3JAK2EGFRJAK1TTK | |
| SCHEMBL17209776 | 0.92 | JAK3 (1.00) | JAK3JAK2EGFRJAK1TTK | |
| SCHEMBL17209790 | 0.92 | JAK3 (1.00) | JAK3JAK2EGFRJAK1TTK | |
| SCHEMBL17209896 | 0.91 | JAK3 (1.00) | JAK3JAK2EGFRJAK1TTK | |
| SCHEMBL17209797 | 0.91 | JAK3 (0.86) | JAK3JAK2EGFRJAK1TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4629993-A1 | METHODS OF TREATING MYELOPROLIFERATIVE NEOPLASMS | Kartos Therapeutics (US) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024124240-A1 | METHODS OF TREATING MYELOPROLIFERATIVE NEOPLASMS | KARTOS THERAPEUTICS (US) | 2024-06-13 | — | — | WO | disclosed |