SCHEMBL309255

SCHEMBL309255

Nc1ccc([N+](=O)[O-])c(Cl)c1Cl

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.63
TSHR P16473 5/20 0.50
CYP3A4 P08684 4/20 0.50
ALDH1A1 P00352 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
POLB P06746 1/20 0.50
MAPT P10636 1/20 0.50
ALOX15 P16050 1/20 0.50
MAPK1 P28482 1/20 0.45
GPR35 Q9HC97 1/20 0.44
TTR P02766 1/20 0.44
ALB P02768 1/20 0.44
THRB P10828 1/20 0.44
LMNA P02545 1/20 0.43
PDE7A Q13946 3/20 0.42
RECQL P46063 1/20 0.42
HTR2A P28223 1/20 0.42
HTR2C P28335 1/20 0.42
HTR2B P41595 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentachloronitrobenzene SCHEMBL8886509 0.91 TDP1 (0.53) TDP1TSHRCYP3A4ALDH1A1MEN1
SCHEMBL28391943 0.86 TDP1 (0.81) TDP1TSHRCYP3A4ALDH1A1POLB
SCHEMBL28322482 0.85 TDP1 (0.54) TDP1TSHRCYP3A4ALDH1A1MEN1
SCHEMBL11047029 0.83 TDP1 (0.53) TDP1TSHRCYP3A4ALDH1A1MEN1
SCHEMBL28038852 0.83 TSHR (0.53) TDP1TSHRCYP3A4ALDH1A1MEN1
SCHEMBL8376326 0.82 TDP1 (0.47) TDP1TSHRCYP3A4ALDH1A1MEN1
SCHEMBL10994079 0.82 TDP1 (0.52) TDP1TSHRCYP3A4ALDH1A1MEN1
SCHEMBL27916755 0.82 TDP1 (0.47) TDP1TSHRCYP3A4ALDH1A1MEN1
SCHEMBL29244091 0.82 TDP1 (0.52) TDP1TSHRCYP3A4ALDH1A1MEN1
SCHEMBL532321 0.81 TDP1 (0.50) TDP1TSHRCYP3A4ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107892824-A A kind of preparation method of environment-friendly type azo dispersion dyes 浙江闰土研究院有限公司 2018-04-10 CN claimed
US-5162511-A Nitrosating and diazotizing reagents and reactions GAMBLIN RODGER L (US) 1992-11-10 US claimed
EP-0007482-B1 2-CHLORO-6-NITROANILINES, PROCESS FOR THEIR PREPARATION, THEIR USE, HERBICIDAL COMPOSITIONS CELAMERCK GmbH & Co. KG (DE) 1981-09-16 EP claimed
EP-0007482-A1 2-Chloro-6-nitroanilines, process for their preparation, their use, herbicidal compositions CELAMERCK GmbH & Co. KG (DE) 1980-02-06 EP claimed
CN-122094953-A 1, 3-Dihydro-2H-pyrrolo [3,4-c ] quinoline derivatives as cGAS inhibitors for the treatment of inflammatory and/or autoimmune diseases 2026-05-26 CN disclosed
WO-2025040569-A1 1,3-DIHYDRO-2H-PYRROLO[3,4-C]QUINOLINE DERIVATIVES AS CGAS INHIBITORS FOR THE TREATMENT OF INFLAMMATORY AND/OR AUTOIMMUNE DISEASES KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2025-02-27 WO disclosed
CN-112745237-B 2-arylamine compound and preparation method and application thereof 中国科学院上海药物研究所 2023-06-20 CN disclosed
CN-106614611-B Fungicidal compositions 先正达参股股份有限公司 2022-07-15 CN disclosed
CN-106614612-B Fungicidal compositions 先正达参股股份有限公司 2022-07-15 CN disclosed
CN-106614620-B Fungicidal compositions 先正达参股股份有限公司 2022-07-15 CN disclosed
CN-112745237-A 2-arylamine compound and preparation method and application thereof 中国科学院上海药物研究所 2021-05-04 CN disclosed
CN-107022509-B Separation method and application of lactobacillus composition 塔里木大学 2021-04-02 CN disclosed
EP-0282951-A2 Controlled release preparations of active materials NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-09-21 EP disclosed
US-4605767-A Process for the preparation of 2,6-dichloro-4-nitroaniline HOECHST AKTIENGESELLSCHAFT (DE) 1986-08-12 US disclosed
US-4239708-A P-Phenylene bis[imino(thiocarbonyl)] diphosphoramidic acid esters as anthelmentic agents AMERICAN CYANAMID COMPANY (US) 1980-12-16 US disclosed
US-4137310-A LARVICIDES AMERICAN CYANAMID COMPANY (US) 1979-01-30 US disclosed
US-4065430-A Functional group containing polymer and method of preparing the same FUJI PHOTO FILM CO., LTD. (JA) 1977-12-27 US disclosed
US-4041017-A Reactive light-sensitive high polymer compound containing furyl pentadienic ester groups and insolubilized by action of heat, light or electron beams FUJI PHOTO FILM CO., LTD. (JA) 1977-08-09 US disclosed
US-3933885-A Cinnamylideneacetic acid esters FUJI PHOTO FILM CO., LTD. (JA) 1976-01-20 US disclosed
US-3931248-A Reactive high polymer compound FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US disclosed