Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10994079 | 0.86 | TDP1 (0.52) | TSHRTDP1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL1683191 | 0.83 | TSHR (0.57) | TSHRTDP1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL309255 | 0.83 | TDP1 (0.63) | TSHRTDP1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL11034572 | 0.82 | TDP1 (0.50) | TSHRTDP1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL768285 | 0.82 | TDP1 (0.54) | TSHRTDP1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL29796095 | 0.82 | TDP1 (0.54) | TSHRTDP1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL588286 | 0.82 | TSHR (0.55) | TSHRTDP1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL278506 | 0.82 | TDP1 (0.67) | TSHRTDP1CYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL30256667 | 0.82 | TDP1 (0.67) | TSHRTDP1CYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL28322482 | 0.82 | TDP1 (0.54) | TSHRTDP1CYP3A4ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175284-A | Amide compounds, preparation method and medical use thereof | UNIV CHINA PHARMA | 2015-12-23 | — | — | CN | disclosed |