Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.55 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24993390 | 1.00 | ALDH1A1 (0.55) | ALDH1A1HPGDCYP2C19CYP1A2GAA | |
| SCHEMBL29214896 | 1.00 | ALDH1A1 (0.55) | ALDH1A1HPGDCYP2C19CYP1A2GAA | |
| SCHEMBL30925901 | 0.96 | ALDH1A1 (0.57) | ALDH1A1HPGDCYP2C19CYP1A2GAA | |
| SCHEMBL24993513 | 0.96 | ALDH1A1 (0.57) | ALDH1A1HPGDCYP2C19CYP1A2GAA | |
| SCHEMBL29214942 | 0.96 | ALDH1A1 (0.57) | ALDH1A1HPGDCYP2C19CYP1A2GAA | |
| SCHEMBL29215121 | 0.93 | HPGD (0.53) | ALDH1A1HPGDCYP2C19CYP1A2GAA | |
| SCHEMBL24993392 | 0.93 | HPGD (0.53) | ALDH1A1HPGDCYP2C19CYP1A2GAA | |
| SCHEMBL24993400 | 0.92 | HPGD (0.63) | ALDH1A1HPGDCYP2C19CYP1A2GAA | |
| SCHEMBL29214775 | 0.92 | HPGD (0.63) | ALDH1A1HPGDCYP2C19CYP1A2GAA | |
| SCHEMBL24993618 | 0.92 | SCN2A (0.55) | ALDH1A1HPGDCYP2C19CYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076348-A | N-acylhydrazone compounds capable of inhibiting NAV 1.7 and/or NAV 1.8, methods of making, compositions, uses, methods of treatment and kits using the same | 欧罗法玛实验室股份公司 | 2024-05-24 | — | — | CN | claimed |
| CN-118076348-A | N-acylhydrazone compounds capable of inhibiting NAV 1.7 and/or NAV 1.8, methods of making, compositions, uses, methods of treatment and kits using the same | 欧罗法玛实验室股份公司 | 2024-05-24 | — | — | CN | disclosed |